{"id":30,"date":"2021-08-13T17:15:29","date_gmt":"2021-08-13T17:15:29","guid":{"rendered":"https:\/\/kaviaari.kapsi.fi\/wordpress\/?page_id=30"},"modified":"2021-08-18T00:23:20","modified_gmt":"2021-08-18T00:23:20","slug":"research","status":"publish","type":"page","link":"https:\/\/kaviaari.kapsi.fi\/wordpress\/research\/","title":{"rendered":"Research"},"content":{"rendered":"\n

The ETOS group operates at the interface between experimental and computer-assisted organic synthesis. Our work is largely driven by inspiration drawn from polycylic alkaloid natural products<\/strong> which are used as platforms for development of new synthetic methods and the study of mechanistically intriguing processes.<\/p>\n\n\n\n

Organic Synthetic Chemistry<\/strong><\/h4>\n\n\n\n

Organic synthetic reactions should be readily accessible to the entire scientific community, allowing people to easily make the molecules they need. This is why we are interested in the development of reliable bench-stable reagents<\/strong>, and spot-to-spot open-flask synthetic methods<\/strong>. To foster new synthetic ideas and to truly acid-test the limitations of current chemistry, we are pursuing the development of ideal syntheses for polycylic alkaloids<\/strong>. In particular, we are interested in the synthesis and biology of structurally unique and highly rare racemic alkaloids.<\/p>\n\n\n\n

The overarching theme in all of our research efforts is the fundamental physical understanding <\/em>of the chemical processes involved. With deeper understanding of underlying regio- and stereoselectivity elements comes greater control over the chemistry at hand. In the long run, we hope such an approach of combining synthesis with computational tools on a fundamental level will provide chemists with reliable tools for a-priori <\/em>prediction even in the realm of dauntingly complex natural product syntheses.<\/p>\n\n\n\n

Relevant publications:<\/p>\n\n\n\n